Structural Elucidation

Identifying unknown impurities and metabolites

The marriage of significant analytical capabilities with the experience of our scientific personnel allows for the isolation and characterization of sub-microgram quantities of impurities during process optimization and purified materials.


Crystallization: increase the relative amount of impurity in mother liquor

Biotage and ISCO preparative normal and reverse phase LC

Forced Degradation: increase impurity level

Waters Preparative LC-UV-MS with mass-directed capabilities

Crystallization: suitable for single crystal X-ray analysis

Impurity Synthesis

Personnel and Experience

3 NMR Spectroscopists (82 years collective experience)

1 Single Crystal Diffractometer Expert (25 years experience)

35 Process Chemists

10 Analytical Chemists

7 Crystallization scientists


4 x NMR systems (1 x 300 MHz / 2 x 400 MHz / 1 x 500 MHz)

>30 HPLC/UPLC systems and 4 CAD units

7 x HPLC/UPLC-MS and 3 x GM-MS

1 x UPLC-Orbitrap MS (accurate mass) new in 2018

Single Crystal X-ray Diffractometer new in 2018

In This Section:
    Add a header to begin generating the table of contents

    Connect With Us

    J-STAR Research helps pharmaceutical small molecule R&D programs succeed in all phases of development.