Senior Research Scientist II – Chemical/Process Engineer

We now have exciting opportunities for Senior Research Scientists to join our vibrant and growing group, with the successful candidates joining a cutting edge CRO with access to gloveboxes, high throughput experimentation, in-situ reaction monitoring tools and state of the art analytical equipment. The primary role responsibility is to perform scale-up of flow chemical reactions, process development, optimization, scale-up and manufacturing in support of J-Star’s Enabling Technologies projects. The incumbent should provide the expertise in the scaleup requirements of flow chemical processes and manufacturing process development.

Prerequisites

  • Experience within the pharmaceutical/biotechnology industry or CDMO industry is required. Experience in both is desirable, but not required.
  • PhD in Process Engineering or Chemical Engineering with a minimum of 2 years of industrial experience or a MS with a minimum of 8 years industrial experience is required.

Responsibilities

  • Conduct chemical engineering R&D for clients as an individual contributor, which includes, but is not limited to, scale-up of chemical reactions in flow and batch mode, conduct experiments to investigate effects of mixing and heat and mass transfer, reaction modeling, statistics & DoE, enabling technologies. This will include R&D under c-GLP and potentially under c-GMP conditions.
  • Contribute to the adoption and operation of new flow technology.
  • Contribute to the expansion of flow chemistry from R&D to process scale up, flow-photochemistry and multiphasic reactions.
  • Contribute to the development of safe, timely and efficient chemical processes by using established, new and/or novel chemical technologies and processes.
  • Contribute chemical engineering methodology to process and/or catalysis development, optimization and problem solving.
  • Maintain an uncompromising focus on quality, documentation, confidentiality, and scientific execution.
  • Adhere to R&D, processing schedules and deliverables.
  • Contribute to scientific and technical discussions with co-workers and clients to plan, execute, resolve issues and problem solve.
  • Contribute to scientific and technical discussions with co-workers and clients to plan, execute, resolve issues and problem solve.
  • Communicate candidly, clearly and timely with clients, management and peers.
  • Participate in weekly client updates as needed, prepare weekly reports, contribute to campaign reports and participate in process chemistry technology transfer.
  • Follow all company, site and laboratory Environmental, Health and Safety (EHS)-related protocols, processes, guidelines and SOPs. Actively participate in EHS discussions with peers and management for continuous improvement of EHS practices.
  • Maintain a clean and well-organized hood, bench, glovebox and common work area that is free of clutter, excess chemicals/samples.

Qualifications

  • Experienced in the fundamental principle of chemical engineering related to scale-up of flow and batch chemistry, specifically reaction kinetics, reactor design, chemical thermodynamics, heat and mass transport, engineering statistics.
  • Experienced using DynoChem, Reaction Lab, MixIt or other modeling software.
  • Experienced with in-situ reaction monitoring like hydrogen uptake kinetics, ReactIR or Raman.
  • Knowledge of statistics and Design of Experiment principles using tools like JMP or Design Expert.
  • A good foundational understanding of synthetic organic chemistry.
  • Proven track record meeting aggressive targets as related to safe, timely and successful synthetic organic chemistry projects.
  • Knowledge and experience base of working in a c-GMP environment is preferable, but not required
  • Excellent written, verbal and presentation skills.
  • Experience in small molecule drug development is preferable, but not required.
  • Track record of scientific success as measured by publications and presentations.
  • Ability to prioritize and manage numerous activities simultaneously.
  • Ability to interact in an effective and appropriate manner with diverse population sets.
  • Experience in working on and positively contributing to scientific teams.
  • Ability to perform the physical requirements of the position.
  • Proficient in Microsoft®Office™ applications.

Reporting Relationship

  • Reports to a Vice President, Director, Associate Director or Sr. Process Chemist (Principal Scientist)

Primary Location: New Jersey, USA
Employee Status: Individual Contributor
Job Type: Full Time/Salaried

Job Location: New Jersey

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