Research Scientist

Research Scientist wanted for J-Star Research Inc in Cranbury, New Jersey, with Master’s degree in Chemistry, Chemical Engineering, or Materials Science and Engineering, and at least one year of experience in the pharmaceutical industry. Must have knowledge of FDA regulations, Polymorph characterization, crystallization, distillation, quantitative analysis, Thermo-Property test, HPLC, UPLC, IC, LC-MS, Methodology Development, and column chromatography. Job duties to be performed:

• Perform Active Pharmaceutical Ingredient (API) crystallization process in compliance with cGMP and FDA regulations, utilizing polymorph and physical properties analytical tools, including spectroscopy, microstructure monitoring, separation, and solvent selection.
• Conduct crystallization process development by conducting studies involving materials engineering and experimental design; Generate materials for pharmaceutical research.
• Participate in the scale-up development of enabling technology and experiments to facilitate the co-processing and development of API.
• Conduct routine stability, performance, and evaluation studies for solid state characterization and pre-formulation support using Polymorph characterization.
• Conduct early drug crystallization process development for high potency compounds and controlled substances.
• Purify pharmaceutical compounds using column chromatography, crystallization, trituration, extraction, and distillation.
• Utilize experimental and simulation/modeling approaches to perform solvent selection and solve process challenges arisen from scale-up crystallization process.
• Analyze organic and inorganic compounds to determine chemical or physical properties, composition, structure, relationships, reactions, using chromatography, spectroscopy, spectrophotometry techniques, and Thermo-Property Test including HPLC, UPLC, SEM, PSD, GC, MS, UV, PXRD, DSC, TGA, NMR, and KF.
• Maintain laboratory instruments to ensure proper working order. Apply scientific expertise to troubleshooting, laboratory investigation and problem resolution.
• Write/review developmental chemistry, process optimization and process scale-up reports to support FDA requirements for CMC (Chemistry, Manufacturing and Control) sections of INDs/NDAs.

Please send resume to HR@JSTAR-Research.com using subject line: ZS-Research Scientist/J-Star Research Inc.