Drug Development
- Improved Access to the Core Scaffolds
- Optimize Problem Points
At J-STAR, every project benefits from the collective expertise of world-class scientists and decades of hands-on experience in the pharma industry. Our team is uniquely positioned to deliver high-quality solutions tailored to the specific needs of our clients, leveraging innovative approaches and cutting-edge technology to meet stringent timelines.
Our team is uniquely positioned to deliver high-quality solutions tailored to the specific needs of our clients.
Leveraging innovative approaches and cutting-edge technology to meet stringent timelines.
As a trusted leader in the field, we also specialize in potent and high-potent compound handling, employing state-of-the-art equipment to tackle the most challenging projects.
J-STAR’s offerings span a wide array of critical areas, from Process Chemistry Research & Development and Drug Product Development to Crystallization R&D and Analytical R&D and Quality Control.
The reasonable predictions produced through computational investigation can help guide reaction development by understanding non-trivial molecular interactions.
Using these predictions, J-STAR Research scientists can gain deeper mechanistic insight, rationalize experimental observations, and identify improved strategies and routes towards their targeted molecules.
Drug Development
Candidate Confirm
First-in-human (FIH) Enabling Toxicology Aupplies
CGMP Clinical Supplies
IND Filing Date
Large-Scale Manufacturing
Founded in 1996 J-STAR Research, Inc. is a contract process R&D and cGMP manufacturing organization serving as an outsourcing partner for the pharmaceutical and biotechnology industry.
Over the past 29 years, J-STAR has assembled a team of chemists, scientists and engineers committed to creatively solving complex and matrixed chemistry and formulation problems.
At J-STAR, every project benefits from the collective expertise of world-class scientists and decades of hands-on experience in the pharma industry. Our team is uniquely positioned to deliver high-quality solutions tailored to the specific needs of our clients, leveraging innovative approaches and cutting-edge technology to meet stringent timelines.
Our team is uniquely positioned to deliver high-quality solutions tailored to the specific needs of our clients.
Leveraging innovative approaches and cutting-edge technology to meet stringent timelines.
As a trusted leader in the field, we also specialize in potent and high-potent compound handling, employing state-of-the-art equipment to tackle the most challenging projects.
While high quality synthetic chemistry and process research services continue to be at J-STAR’s foundation, the company has steadily added, and continues to expand, in the following areas:
Client medicinal chemistry processes commonly face multiple risks and challenges, including:
J-STAR understands that when a synthesis contains too many of these challenges, the cost of that compound can become extremely expensive—for example, even a few hundred grams could escalate costs to over 1 million USD!
Client medicinal chemistry processes commonly face multiple risks and challenges, including:
J-STAR understands that when a synthesis contains too many of these challenges, the cost of that compound can become extremely expensive—for example, even a few hundred grams could escalate costs to over 1 million USD!
Using up to 24-cores/48-threads and 192GB of RAM, the computational resources at J-STAR Research provides a wide range of capabilities.
Properties that can be predicted from computational models include:
In addition to molecular properties, entire or partial reaction pathways can be examined at the molecular scale predicting values like activation energy and site reactivity, giving insights into reaction kinetics, transition states, reaction orders, product distributions and more.
The reasonable predictions produced through computational investigation can help guide reaction development by understanding non-trivial molecular interactions.
Using these predictions, J-STAR Research scientists can gain deeper mechanistic insight, rationalize experimental observations, and identify improved strategies and routes towards their targeted molecules.
Better understanding of structures and properties of working catalysts
Computational chemistry aids in the first principal driven development of our processes.
Integrated in route scouting, optimization of reactions, better understanding of structures and properties of working catalysts, computational chemistry aids in the first principal driven development of our processes.
Using relatively routine methods, our skilled computational chemists can provide predictions that are close to experimental data with proper considerations of methods and basis sets of various important chemical properties, strongly complementing classical experimental results.
Predictions that are close to experimental data with proper considerations of methods
Basis sets of various important chemical properties
Strongly complementing classical experimental results.