- We offer all of our services as a standalone service or integral with our other services (Synthesis, process development, GMP manufacturing and crystallization).
- Development planning: We provide an individualized work proposal that suits the needs of the customer (early development vs. manufacturing process or fit for purpose vs. optimized for efficiency).
- Scouting and Screening: We support the early development for route selection utilizing our High-Throughput platform.
- Synthesis: Supporting early drug development by synthesizing API libraries (96 well)
- Optimization: We optimize reactions using various tools, which can encompass our High-Throughput platform in combination with DoE, kinetic DoE, Bayesian optimization and improving catalyst performance through mechanistic understanding.
- Operational evaluation: Evaluate a specific reaction for batch, semi-batch and flow operation.
- Process stability: Identification of best operational procedures, stable holding points and most stable operating range.
- Scale-up: The reaction is being scaled-up under best engineering consideration and representative scalable procedures considering mixing and mass-transfer.
- Reaction Safety: Isocratic reaction calorimetry, adiabatic temperature rise calculation, gas evolution measurement.
- Efficient technology transfer: Throughout the collaboration the results are frequently communicated in written reports and through teleconferences. A final report can be issued summarizing all relevant information in an updated context of the final development stage.
