Are you facing the challenge of getting reliable single crystal structures of API or intermediate compounds?

You can get professional help from our leading crystallization expert with decades of successful experience from BMS and the Center for Pharma Crystallization (CfPC) at J-STAR Research.

In the past 5 years, more than 200 single crystal structures have been elucidated in support of fast-paced new drug development programs. Many of these compounds are extremely challenging to grow high quality crystals sufficient for reliable structure elucidation.

The utilities of crystal structure elucidation, which are multi-faceted as highlighted below, support different aspects of a drug development program:

• Crystal Structure Determination (Composition, Confirmation & Configuration) for Patent Applications and Regulatory Fillings.
• Understanding of Solid-state Properties from Crystal Structure Perspective (Crystal Packing, Hydrogen Bonding, Intermolecular Interactions etc.).
• Relative Stability Investigation of Different Polymorphs.
• Simulation of PXRD Pattern Used as the "Gold Standard" Reference for Crystal Form Identification.
• Crystal Structure Used as Inputs in Predictions, Such as Agglomeration,  Morphology Optimization & Mechanical Properties