Novel Technology Platforms

A highly detailed scientific illustration showcases microscopic cells and viruses under a microscope, featuring the text "PORTON" and "#Anything Can Be Conjugated" in the top corners. This intriguing case study explores the interaction of antibody oligonucleotide conjugates at a cellular level.

Exploring Antibody Oligonucleotide Conjugates: Insights and Case Study

In the field of biomedical science, technological changes are common and constantly evolving. In recent years, antibody oligonucleotide conjugates (AOCs) have attracted considerable attention in the industry as an innovative and advanced biomedical method, and more and more domestic and…

A person in orange gloves operates laboratory equipment with glass containers and red tubing, using a digital tablet to ensure continuous improvement. The word "Porton" is visible on the wall, symbolizing precision and innovation throughout the project life cycle management process.

Improving Project Life Cycle Management to Reduce Customer Costs

The project life cycle is the phases of a project that are necessary for the effective delivery of that project.

Porton’s project life cycle management (LCM) involves establishing mid and long-term plans for key projects to ensure the timing and …

A cluster of interconnected, translucent spheres with reflections, set against a blue background, suggesting the harmony of high-throughput experimentation. The top left features the text "Porton J-Star.

Asymmetric Synthesis of ENT-03 via Hydrogenation and High-Throughput

ENT-03 was predicted to be the mammalian equivalent of trodusquemine, based on knowledge of the bile acids produced in mammals, such as 7-HOCA. The individual C-25 isomers of ENT-03 were prepared and both detected in mouse brain. Trodusquemine and ENT-03 …

Molecular structures float in a purple environment, with the text "Anything Can Be Conjugated" alongside the logo "PORTON" in the top left corner, hinting at innovative ADC solutions and seamless process scale-up.

Navigating ADC Market Entry: Key Challenges and Solutions

An Antibody Drug Conjugate ( is a novel therapeutic agent which can deliver a highly potent traditional small molecule drug to a specific site or cell within the body It is formed when an active drug (the payload) is connected …

A scientist in blue gloves uses a pipette in a lab focused on pharmaceutical development, with scientific formulas and molecular modeling diagrams adorning the whiteboard in the background.

Molecular Modeling and Data Science for Affordable Pharma Development

With advances in computational materials science and process simulation, computational applications are becoming an integral part of the drug development and manufacturing workflow.1,2 These methods facilitate easier navigation through the complex multidimensional space of pharmaceutical process development tasks. By combining …

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Dry Particle Coating: Enhancing Flowability and Bulk Density Solutions

Many active pharmaceutical ingredients (API) exhibit deficient bulk powder properties such as poor flowability, low bulk density, high cohesion, etc. These deficiencies may cause some major issues for the performance of downstream processing including the blending, content uniformity, and tablet …

Icon of a blue poster with a large "P" above the word "Poster," set against a white background, featuring a blue and orange curved banner. The design subtly echoes the concept of enhancing flow, akin to dry particle coating methods that optimize powder flow density.

Enhance Powder Flow Density and Flow By Dry Particle Coating

Many active pharmaceutical ingredients (API) exhibit deficient bulk powder properties such as poor flowability, low bulk density, high cohesion, etc. These deficiencies may cause some major issues for the performance of downstream processing thus affect content uniformity in final product.…