Crystallization

Laboratory equipment collage featuring robotic arms, test tubes with red liquid, electronic devices, and mineral samples, all set against a backdrop of single crystal structure analysis.

Single Crystal Structure Elucidation (media)

Center for Pharma Crystallization

J-STAR Research Inc
6 Cedar Drive, Cranbury, New Jersey 08512

Are you facing challenges getting reliable single crystal structures of APIs or intermediate compounds?

You can get professional help from our leading crystallization expert with …

Aerial view of the CfPC's expansive office complex with multiple interconnected buildings, surrounded by parking lots, green spaces, and a pond on a clear day.

CfPC at J-STAR Research

CfPC at J-STAR Research

Center for Pharma Crystallization, J-STAR Research Inc
6 Cedar Drive, Cranbury, New Jersey 08512

See how the Center for Pharma Crystallization (CfPC) at J-STAR Research is effectively supporting new drug development programs: https://www.jstar-research.com/contract-rd-services/crystallization-rd/…

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Preformulation Strategy – Inception to Completion

 
Drug discovery is an exceedingly complex process. Discovering a new chemical entity is in itself a huge accomplishment, which is often possible only after almost two decades of hard experimental work as well as advanced simulation efforts. Therefore, the next …

Icon of a film strip with a play button inside and the word "VIDEO" underneath, set against orange and blue curved stripes reminiscent of detailed Nano-API crystallization patterns.

Mastering Controlled Nano-API Crystallization and Isolation Techniques


Don Kientzler

Center for Pharma Crystallization, J-STAR Research Inc
6 Cedar Drive, Cranbury, New Jersey 08512

Abstract

Controlled crystallization of an API in submicron size was enabled based on an accurate solubility profile and a growth inhibition property via semi-continuous …

Icon of a film strip with a play button inside and the word "VIDEO" underneath, set against orange and blue curved stripes reminiscent of detailed Nano-API crystallization patterns.

Overcoming Crystallization Bottlenecks in New Drug Development

Jian Wang

Center for Pharma Crystallization, J-STAR Research Inc
6 Cedar Drive, Cranbury, New Jersey 08512
Abstract

Diverse crystallization challenges encountered by CfPC (Center for Pharma Crystallization) and our clients will be analyzed systematically to provide insights into main bottleneck …

Icon of a film strip with a play button inside and the word "VIDEO" underneath, set against orange and blue curved stripes reminiscent of detailed Nano-API crystallization patterns.

Optimizing Pharmaceutical Crystallization with Computational Methods

Yuriy A. Abramov

yuriy.abramov@xtalpi.com
XtalPi Inc, Cambridge MA, USA.
Abstract

Given challenges facing the pharmaceutical industry, an accelerated Drug Development greatly benefits from guidance provided by computational methods.1 This presentation will focus on computational support of the following important tasks …

A blue report icon with a line graph sits above the word "REPORT" in orange, evoking a sense of clarity and precision akin to scientific processes. Orange and blue curved stripes at the top add a dynamic flow, reminiscent of data trends discussed at a pharmaceutical summit.

2020 Pharmaceutical Crystallization Summit Report

Crystallization technologies are bridges between drug substances (DS) and drug products (DP) enabling consistent and robust safety and efficacy profiles of small molecule based medicines. In an effort to fully utilize existing tools and develop better new method-logies for solving …

Icon of a film strip with a play button inside and the word "VIDEO" underneath, set against orange and blue curved stripes reminiscent of detailed Nano-API crystallization patterns.

Strategies for Addressing Pharmaceutical Crystallization Challenges

Dr. William Glauser

XtalPi, Inc., USA
Abstract

Problems associated with polymorphic instability and increasingly insoluble drug candidates represent white space to innovate novel forms and processing methods with better properties in the drug product. But the journey from identifying new …

Icon of a film strip with a play button inside and the word "VIDEO" underneath, set against orange and blue curved stripes reminiscent of detailed Nano-API crystallization patterns.

Optimizing Solvent Selection for Crystal Form Investigations


Dr. Shanming Kuang

Center for Pharma Crystallization, J-STAR Research Inc
6 Cedar Drive, Cranbury, New Jersey 08512
shanming.kuang@jstar-research.com

Abstract

Rational selection of solvents plays a critical role in solid form screening and production. On the one hand, a variety of …