Contract Research Organization (CRO):  

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The J-Star Research facility occupies 28,000 square feet of leased space in South Plainfield, NJ. A partial listing of some of the Analytical Instrumentation and Specialized Equipment is given below:

Analytical Instrumentation

     ▪     Varian Inova NMR Systems, 300 and 400 MHz;

     ▪     HPLC / UPLC (Agilent 1260, 1100, Thermo Ultimate 3000 – UV / CAD / ELSD)

     ▪     LC / MS (Thermo Finnigan Surveyor MSQ Plus Mass Spectrometer)

     ▪     GC / FID (Agilent 6890 with headspace and direct injection)

     ▪     GC-MS (Agilent 6890)

     ▪     Dionex Ion Chromatography

     ▪     FT-IR Spectrometer (Nicolet Avatar 360)

     ▪     OptiMelt Automated Melting Point;

     ▪     Metrohm 756 KF Coulometer with sample oven;

     ▪     Accumet XL-15 pH Meter;

     ▪     Polarimeter (PerkinElmer 341)

     ▪     TGA (TA Discovery Series)

     ▪     DSC (TA Discovery Series)

     ▪     Particle Size Analyzer (Horiba LA-920 PSD)

     ▪     Polarized Light Microscopy (Olympus SZX 12);

     ▪     Rikagu MiniFlex 600 XRPD

Specialized Equipment

     ▪     Multiple Automated Flash Chromatography Equipment up to 340 gram cartridges

     ▪     Biotage Isolera Automated Flash Chromatography System for larger scale chromatography up to 1.5 kg cartridges

     ▪     Initiator Microwave

     ▪     Stability Chambers

     ▪     Photostability Chamber

     ▪     Flash Chromatography Systems: Biotage Flash 75 and Flash 150

     ▪     Multiple Buchi 20L Evaporators

     ▪     High pressure (2000 psi) stainless steel hydrogenation vessels, up to 8 Liter

     ▪     Glass reaction vessels up to 100 Liter

     ▪     Medium pressure (50 psi) glass reaction vessels up to 5 Liter

     ▪     Waters Delta Prep 4000 with Varian Load and Lock Columns up to 3”

     ▪     Virtis Lyopholizer (5 L, 15L, and 25L)

     ▪     Beckmann Refrigerated Centrifuge, 1 Liter

     ▪     Vacuum ovens, 0.5 to 4.5 cu. ft.

     ▪     Multiple Jacketed Glass reaction vessels up to 100 Liter

     ▪     Large Flash chromatography columns, up to 10” x 48”

     ▪     Ozonolysis Equipment

     ▪     Walk-in Refrigerator

     ▪     Solvent Storage in a vented, cinder block vault with explosion proof fixtures

     ▪     Mettler Toledo S400 FBRM (in-situ Focused Beam Refectence Measurement, 2 sets with 3 probes);

     ▪     Mettler Toledo OptiMax (automated reactor with calorimetry)

     ▪     Mettler Toledo EasyMax(automated parallel reactors with temperature and mixing controls);

     ▪     Olympus SZX 12 Polarized Light Microscopy;

Chemical Library

The company has subscriptions to SciFinder and Beilstein for on-line literature searching and ACD for on-line sourcing of smaller quantities of raw materials. We also maintain subscriptions to numerous chemistry journals with on-line access.

As a value-added service, J-Star acquired the entire chemistry library from American Cyanamid, including eighty one complete collections of leading chemistry journals spanning the years from 1876 to 2001.

This impressive collection includes a complete collection of Organic Reactions, Comprehensive Heterocyclic Chemistry, Comprehensive Organic Chemistry (Trost series), Angewandte Chemie, Int. Ed., Journal of The American Society, Journal of The Chemical Society (including Chemical Communications and Perkin Transactions), Journal of Medicinal Chemistry, Journal of Organic Chemistry, Tetrahedron Letters, and many others.