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Category : PCS2022

A new approach to stere-opure atropisomeric molecules enabled by continuous flow-crystallization

By Dr. Michal Achmatowicz, Mirati Therapeutics Abstract: A new approach to stereopure atropisomeric molecules is enabled by a continuous flow-crystallization process. Continuous accumulation of the product under its optimal...

Dr. Michal Achmatowicz, Mirati Therapeutics

Dr. Michal Achmatowicz received Ph.D. in organic chemistry in 2001 after working with Prof. Janusz Jurczak at the University of Warsaw and the Institute of Organic Chemistry of the...

Combined In-Silico & Experimental Approach for Solid Form Screen & Selection

By Drs. Yuriy Abramov and Shanming Kuang, Center for Pharma Crystallization, J-Star Research Small molecule drug candidates tend to have different solid forms, including anhydrate, hydrate, solvate, salt, cocrystal...

Dr. Shanming Kuang, J-Stat Research/ Porton

Dr. Shanming Kuang is currently the Head of Center for Pharma Crystallization at Porton Shanghai and Senior Director of Solid Form Studies at J-Stat Research. Shanming obtained his PhD...

Dr. Yuriy Abramov, J-Star Research

Dr. Yuriy Abramov is an industrial computational scientist with over 18 years experience at Pfizer Inc. Currently he holds a position of an Executive Director of computational chemistry and...

Dr. Nima Yazdanpanah, Procegence

Dr. Nima Yazdanpanah is a consultant on advanced manufacturing and modeling and simulation applications in Bio/pharmaceutical and fine chemical industries. His area of expertise covers process simulation, particulate matters,...

Simulation Aided Process/Product Development, Scale-up, Tech-Transfer, and Regulatory Submission

By Dr. Nima Yazdanpanah, Consultant, Procegence Mechanistic modelling and process simulation, based on first-principle analysis, is a well-practiced tool in the chemical industry. The diverse applications have been enabled...

Dr. San Kiang, J-Star Research / Porton

Currently Chief Technology Officer at Porton Pharmatech/J-Star Research, Inc. San Kiang is an SME in continuous processing API, continuous processing DP, particle engineering, pharmaceutical composite material, co-processing and pharmaceutical...

Enabling Technologies for Tox/FIH Formulation

By Dr. San Kiang, J-Star Research / Porton The business goal of most CMC development is to reach FIH as fast as possible. However, before IND or Phase 1,...

Novel analytical methods and insights into Amorphous Solid Dispersions

By Dr. Simon Bates, Rigaku Americas Corp X-ray powder diffraction has been the gold standard for solid state pharmaceutical analysis for quite some time. However, when it comes to...

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